drugset / Trial / NCT07454642

AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors

NCT07454642 ↗

Phase 1 Recruiting 174 enrolled Avacta Life Sciences Ltd
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a first-in-human (FIH), Phase 1 open-label, multicenter dose escalation study investigating AVA6103 monotherapy administered intravenously in patients with locally advanced (unresectable) or metastatic solid tumors that are likely to be FAP positive. The study consists of an initial Phase 1a dose escalation portion and a subsequent Phase 1b dose expansion portion upon completion of the dose escalation portion.

Timeline

Start
2026-03-31
Primary completion
2029-01
Completion
2030-06

Drugs

EvaluationDrugModalityDoseRoute
Subject AVA6103 Unknown — Intravenous