drugset / Trial / NCT07460206

Pembrolizumab Plus Lenvatinib in REcurrent ccRCC Patients Failing permbroLizUmab aDjuvant trEatment

NCT07460206

Phase 2 Not yet recruiting 108 enrolled Italian Oncology Group for Clinical Research
NaSingle-groupOpen-labelTreatment

Summary

This study is being performed as a single-arm open-label study in order to provide information on the potential benefits of the combination of pembrolizumab and lenvatinib in participants with advanced ccRCC who have progressed on Pembrolizumab as their prior therapy in the adjuvant RCC setting.

Timeline

Start
2026-08
Primary completion
2031-08
Completion
2031-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenvatinib Small molecule 20 mg Oral
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous