drugset / Trial / NCT07463183

A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)

NCT07463183 ↗

Phase 2 Recruiting 100 enrolled Merck Sharp & Dohme LLC
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this protocol is to evaluate the efficacy of MK-8690 in participants with moderately to severely active ulcerative colitis. The primary hypothesis is that MK-8690 is superior to placebo with respect to the proportion of participants achieving clinical remission per Modified Mayo Score at Week 12.

Timeline

Start
2026-03-24
Primary completion
2027-10-28
Completion
2028-12-21

Drugs

EvaluationDrugModalityDoseRoute
Subject MK-8690 Unknown — Subcutaneous

Indications