drugset / Trial / NCT07463599

Safety and Efficacy of Tegavivint in Patients With Metastatic Colorectal Carcinoma

NCT07463599

Non-randomizedSequentialOpen-labelTreatment

Summary

This trial will evaluate the safety, tolerability, and preliminary efficacy of tegavivint as monotherapy (single) and in combination with standard therapies in patients with metastatic colorectal carcinoma (mCRC).

Timeline

Start
2026-02-17
Primary completion
2029-01
Completion
2029-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Tegavivint Small molecule 5 mg/kg Intravenous
Subject Tegavivint Small molecule 6.5 mg/kg Intravenous
Subject Tegavivint Small molecule 8 mg/kg Intravenous
Subject Tegavivint Small molecule 10 mg/kg Intravenous

Indications