drugset / Trial / NCT07466303

Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast Cancer

NCT07466303

Phase 2 Not yet recruiting 84 enrolled Xijing Hospital
NaSingle-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of Serplulimab in combination with Trastuzumab Restuzumab for the neoadjuvant treatment of triple-negative breast cancer, aiming to provide evidence for optimizing the strategy of combining immunotherapy with ADC drugs in the neoadjuvant setting.

Timeline

Start
2026-03-25
Primary completion
2028-02-01
Completion
2031-04-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Serplulimab Monoclonal antibody Intravenous
Subject Trastuzumab Rezetecan Monoclonal antibody Intravenous