drugset / Trial / NCT07468513
Primaquine for Vivax Malaria in G6PD Intermediate and Deficient Cases.
Phase 4
Recruiting
100 enrolled
Menzies School of Health Research
Arba Minch University · collabCurtin University · collabIndonesia University · collabMahidol Oxford Tropical Medicine Research Unit · collabOxford University Clinical Research Unit, Vietnam · collabPapua New Guinea Institute of Medical Research · collabUniversity of Melbourne · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
A non randomized observation study that is aiming to assess the safety and efficacy of high dose primaquine (1mg/kg per day over 7 days) among patients with intermediate (30-70%) G6PD activity and the safety and efficacy of weekly primaquine among patients who are g6Pd deficient (\<30% activity)
Timeline
- Start
- 2024-05-17
- Primary completion
- 2028-06-30
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Primaquine | Small molecule | 0.75 mg/kg | — |
| Comparator | Primaquine | Small molecule | 1 mg/kg | — |