drugset / Trial / NCT07475182

Exploratory Clinical Study of Targeted Activated DC and CAR-T Therapy in Advanced Solid Cancers

NCT07475182 ↗

NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, single-arm clinical study designed to evaluate the safety and preliminary efficacy of Targeted Activated DC combined with CAR-T therapy in patients with Advanced Solid Cancers.This combination therapy activates dendritic cells (DCs) to precisely target the tumor site, reshaping the tumor immune microenvironment, breaking down the immunosuppressive barrier, and allowing CAR-T cells to penetrate deeper into the tumor more efficiently, precisely and persistently killing cancer cells.

Timeline

Start
2025-12-06
Primary completion
2027-12-06
Completion
2028-06-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Targeted Activated Dendritic Cells Cell therapy — —
Subject Targeted CAR-T Cells Cell therapy — —