drugset / Trial / NCT07475949

Unknown Time of Onset Stroke RePerfusIon Without Advanced Imaging

NCT07475949

Phase 3 Not yet recruiting 352 enrolled First Affiliated Hospital of Guangxi Medical University
RandomizedParallel-groupSingle-blindTreatment

Summary

The benefit of intravenous tenecteplase for acute ischemic stroke with unknown time of onset, e.g. wake-up stroke, remains uncertain. This randomized study aims to assess the efficacy and safety of intravenous tenecteplase following non-contrast CT screening for acute ischemic stroke with unknown time of onset.

Timeline

Start
2026-04
Primary completion
2028-12
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Tenecteplase Protein / enzyme biologic 0.25 mg/kg Intravenous

Indications