drugset / Trial / NCT07480382

Safety and Efficacy of LVD + C-TACE + Tis/Len for Unresectable Right-Liver HCC

NCT07480382

Not yet recruiting 30 enrolled Hong Wu
NaSingle-groupOpen-labelTreatment

Summary

This study evaluates a novel "Dual-Conversion" strategy (mechanical volume conversion via LVD plus biological conversion via cTACE, Tislelizumab, and Lenvatinib) for patients with initially unresectable right-sided hepatocellular carcinoma (HCC). The primary goal is to assess the rate of successful conversion to R0 resection and the safety profile of this multi-modal approach.

Timeline

Start
2026-04-01
Primary completion
2027-12-30
Completion
2028-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenvatinib Small molecule 8 mg Oral
Subject Lenvatinib Small molecule 12 mg Oral
Subject Tislelizumab Monoclonal antibody 200 mg Intravenous