drugset / Trial / NCT07483099

A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

NCT07483099

Phase 2 Recruiting 60 enrolled Eli Lilly and Company
RandomizedParallel-groupOpen-labelTreatment

Summary

The main purpose of this study is to see how the safety and efficacy of a farnesoid X receptor (FXR) agonist (LY4395089), given together with mirikizumab compares with mirikizumab (alone) in adults with moderately to severely active Crohn's disease (CD). This study is part of the IIBD master protocol and will last approximately 62 weeks.

Timeline

Start
2026-05-04
Primary completion
2027-06
Completion
2028-03

Drugs

EvaluationDrugModalityDoseRoute
Subject LY4395089 Unknown Oral
Subject Mirikizumab Monoclonal antibody Intravenous

Indications