drugset / Trial / NCT07483099
A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease
RandomizedParallel-groupOpen-labelTreatment
Summary
The main purpose of this study is to see how the safety and efficacy of a farnesoid X receptor (FXR) agonist (LY4395089), given together with mirikizumab compares with mirikizumab (alone) in adults with moderately to severely active Crohn's disease (CD). This study is part of the IIBD master protocol and will last approximately 62 weeks.
Timeline
- Start
- 2026-05-04
- Primary completion
- 2027-06
- Completion
- 2028-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LY4395089 | Unknown | — | Oral |
| Subject | Mirikizumab | Monoclonal antibody | — | Intravenous |