drugset / Trial / NCT07483177
HEART: Pilot Randomized Controlled Trial
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to determine whether spironolactone reduces aortic stiffness, measured by carotid-femoral pulse wave velocity (cfPWV), compared with placebo, in patients with degenerative thoracic aortic aneurysms.
Timeline
- Start
- 2026-05-25
- Primary completion
- 2028-05
- Completion
- 2028-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Spironolactone | Small molecule | 50 mg | — |