drugset / Trial / NCT07483307

A Study of the Impact of Endocrine Therapy on Surgical Outcomes in People With Lobular Breast Cancer

NCT07483307

Phase 2 Recruiting 176 enrolled Memorial Sloan Kettering Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to look at how effective neoadjuvant (before surgery) endocrine therapy (NET) is in participants with invasive lobular carcinoma (ILC) who have breast-conserving surgery (BCS). The main purpose of the study is to see if NET reduces the chance of having cancer cells at the edges of tissue removed during surgery (positive margins).

Timeline

Start
2026-03-13
Primary completion
2030-03-13
Completion
2030-03-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Anastrozole Other / unclassified
Subject Exemestane Small molecule
Subject Letrozole Other / unclassified
Subject Tamoxifen Small molecule