drugset / Trial / NCT07484204

Evaluate Pharmacokinetics, Safety, and Tolerability of AX251 LAI in Patients With Schizophrenia

NCT07484204

Phase 1 Not yet recruiting 48 enrolled Anxo Pharmaceutical Co., Ltd.
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the pharmacokinetics (PK), safety, and tolerability of AX251 long-acting injectable (LAI) administered as a single dose in patients with schizophrenia. The study will include sequential dose-escalation cohorts to evaluate different dose levels of AX251 LAI.

Timeline

Start
2026-07
Primary completion
2028-07
Completion
2028-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cariprazine Small molecule 45 mg
Subject Cariprazine Small molecule 90 mg
Subject Cariprazine Small molecule 135 mg
Subject Cariprazine Small molecule 180 mg

Indications