drugset / Trial / NCT07486869

Emapalumab MDA5 Rapidly Progressive Interstitial Lung Disease (RP-ILD) Study

NCT07486869

Phase 2 Not yet recruiting 5 enrolled University of Miami Swedish Orphan Biovitrum · collab
NaSingle-groupOpen-labelTreatment

Summary

This is a proof of concept study to determine if Emapalumab appears effective for the treatment of anti-MDA5 antibody positive rapidly progressive interstitial lung disease (MDA5 RP-ILD). Emapalumab is a medication that is currently used for a severe problem with the immune system, called macrophage activation syndrome, and this disease shares some similar features with MDA5 RP-ILD.

Timeline

Start
2026-07
Primary completion
2027-05
Completion
2027-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Emapalumab Monoclonal antibody 3 mg/kg Intravenous