drugset / Trial / NCT07489976

IIT2025-03-YANG-LIFT-HCC

NCT07489976

Phase 2 Recruiting 41 enrolled Ju Dong Yang
NaSingle-groupOpen-labelTreatment

Summary

The investigators are doing this study to learn if a combination of immunotherapy and a liver-directed tumor procedure can safely and effectively shrink or control liver cancer (hepatocellular carcinoma, HCC). The goal is to try to lower the stage of the cancer so that more patients may become eligible for a liver transplant. The investigators will also closely watch for side effects from the study treatments. Section 2 has more details.

Timeline

Start
2026-04-01
Primary completion
2030-04-01
Completion
2030-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Durvalumab Monoclonal antibody 1500 mg Intravenous
Subject Tremelimumab Monoclonal antibody 300 mg Intravenous