drugset / Trial / NCT07495813

A Study to See How RO7763505 Works and How Safe it is When Given to Healthy People and People With Stable Heart Disease

NCT07495813 ↗

Phase 1 Recruiting 196 enrolled Hoffmann-La Roche
RandomizedParallel-groupTriple-blindTreatment

Summary

This study will evaluate safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses (SAD) (Part 1a), multiple ascending doses (MAD) (Part 1b), and the food effect (Part 1c) of RO7763505 in healthy adult participant. In Part 2, the safety, tolerability, PK and PD of multiple doses of RO7763505 in participants with stable coronary artery diseases (CAD).

Timeline

Start
2026-03-31
Primary completion
2028-02-15
Completion
2028-02-15

Drugs

EvaluationDrugModalityDoseRoute
Subject RO7763505 Unknown — —