drugset / Trial / NCT07509307

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

NCT07509307

Phase 3 Recruiting 400 enrolled Novo Nordisk A/S
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study is being done to look at the safety and effect of NNC0487-0111 in people with excess body weight and knee osteoarthritis when compared to placebo. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111, (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.

Timeline

Start
2026-04-20
Primary completion
2028-08-14
Completion
2028-08-14

Drugs

EvaluationDrugModalityDoseRoute
Subject NNC0487-0111 Unknown Subcutaneous