drugset / Trial / NCT07511036

PROSECCO: A Phase 2, Single Arm, Neoadjuvant Study Evaluating Combination Cemiplimab, Fianlimab, And Ipilimumab In Patients With Surgically Resectable Melanoma

NCT07511036

Phase 2 Not yet recruiting 20 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

This is a phase II study testing the safety and preliminary efficacy of triplet ICB in treatment naïve patients with clinical stage III or oligometastatic stage IV melanoma with resectable disease.

Timeline

Start
2026-09-01
Primary completion
2028-05-24
Completion
2030-05-24

Drugs

EvaluationDrugModalityDoseRoute
Subject Cemiplimab Monoclonal antibody Intravenous
Subject Fianlimab Monoclonal antibody Intravenous
Subject Ipilimumab Monoclonal antibody Intravenous

Indications