drugset / Trial / NCT07516418
Study of Different Formulations of Vaccines Encoding the RSV Monovalent Antigen or the Flu H5 Antigen in Participants 18 to 49 Years of Age
RandomizedSequentialTriple-blindPrevention
Summary
The purpose of this study is to evaluate the safety and immunogenicity of different formulations of vaccines encoding the RSV monovalent antigen or the Flu hemagglutinin subtype 5 (H5) antigen in healthy participants aged 18 to 49 years. The total duration of study participation for each participant varies by stage and treatment arm. Stage 1: * For Arm 1, Arm 2, and Arm 3 the duration of study participation will be approximately 7 months for each participant. * For Arm 4, Arm 5, and Arm 6 the duration of study participation will be approximately 6 months for each participant. Stage 2: For all arms, the duration of study participation will be approximately 7 months for each participant.
Timeline
- Start
- 2026-04-15
- Primary completion
- 2027-04-04
- Completion
- 2027-04-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | H5 Flu IMP 10 | Vaccine | — | Intramuscular |
| Subject | H5 Flu IMP 11 | Vaccine | — | Intramuscular |
| Subject | H5 Flu IMP 12 | Vaccine | — | Intramuscular |
| Subject | H5 Flu IMP 2 | Vaccine | — | Intramuscular |
| Subject | H5 Flu IMP 3 | Vaccine | — | Intramuscular |
| Subject | H5 Flu IMP 7 | Vaccine | — | Intramuscular |
| Subject | H5 Flu IMP 8 | Vaccine | — | Intramuscular |
| Subject | H5 Flu IMP 9 | Vaccine | — | Intramuscular |
| Subject | H5 Flu Investigational Medical Product (IMP) 1 | Vaccine | — | Intramuscular |
| Subject | RSV IMP 4 | Vaccine | — | Intramuscular |
| Subject | RSV IMP 5 | Vaccine | — | Intramuscular |
| Subject | RSV IMP 6 | Vaccine | — | Intramuscular |