drugset / Trial / NCT07517445
Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary Tuberculosis
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine if nicotinamide in combination with bedaquiline, pretomanid, and linezolid, is safe and effective in treating drug-susceptible pulmonary tuberculosis.
Timeline
- Start
- 2026-04-17
- Primary completion
- 2027-06-14
- Completion
- 2027-06-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bedaquiline | Small molecule | 200 mg | — |
| Comparator | Linezolid | Other / unclassified | 600 mg | — |
| Comparator | Pretomanid | Small molecule | 200 mg | — |