drugset / Trial / NCT07523711

Effect of Maridebart Cafraglutide on How Oral Contraceptives Are Absorbed and Processed in the Body in Postmenopausal Female Participants Living With Overweight or Obesity

NCT07523711

Phase 1 Active not recruiting 49 enrolled Amgen
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The primary objective of the trial is to evaluate the effect of maridebart cafraglutide on the pharmacokinetics (PK) of a combined oral contraceptive (COC) in postmenopausal female participants living with overweight or obesity.

Timeline

Start
2026-04-09
Primary completion
2026-11-18
Completion
2026-11-18

Drugs

EvaluationDrugModalityDoseRoute
Subject Maridebart Cafraglutide Unknown Subcutaneous
Subject Norgestimate Small molecule Oral
Subject ethinyl estradiol Small molecule Oral

Indications