drugset / Trial / NCT07524374

SHR-1701 in Combination With Irinotecan Liposome (II) for Second-line Treatment of ESCC After Immunotherapy

NCT07524374

Phase 2 Not yet recruiting 33 enrolled Zhigang Li Jiangsu HengRui Medicine Co., Ltd. · collab
NaSingle-groupOpen-labelTreatment

Summary

This study is a single-arm, exploratory clinical trial aimed at evaluating the efficacy and safety of SHR-1701 in combination with liposomal irinotecan (II) in patients with esophageal squamous cell carcinoma who have received prior immunotherapy. Eligible patients with esophageal cancer will be treated with SHR-1701 in combination with liposomal irinotecan (II).

Timeline

Start
2026-03-15
Primary completion
2027-09-30
Completion
2028-03-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Irinotecan Small molecule
Subject Retlirafusp alfa Protein / enzyme biologic