drugset / Trial / NCT07525141

A Study of JNJ-1761981 in Participants With Solid Tumors

NCT07525141

Phase 1 Recruiting 66 enrolled Johnson & Johnson Enterprise Innovation Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of Part 1 of this study is to determine a safe, tolerable, and feasible recommended total dose of intratumorally administered JNJ-1761981. The purpose of Part 2 of this study is to identify the optimal volumetric dose of JNJ-1761981 for the treatment of tumor lesions.

Timeline

Start
2026-05-18
Primary completion
2028-01-12
Completion
2029-01-31

Drugs

EvaluationDrugModalityDoseRoute
Subject JNJ-1761981 Unknown Other
Background Cetrelimab Monoclonal antibody Intravenous

Indications