drugset / Trial / NCT07527260

Effects of Adenoidectomy on Symptoms and IgE Levels in Children With AR

NCT07527260

Not yet recruiting 36 enrolled Tongji Hospital
Non-randomizedParallel-groupSingle-blindTreatment

Summary

This study aims to evaluate the effects of conservative management versus surgical intervention (adenoidectomy alone or adenotonsillectomy) on symptoms and local IgE levels in children with allergic rhinitis (AR) accompanied with adenotonsillar hypertrophy. The primary objectives include the impact of conservative management and surgical interventions on AR symptoms and local IgE levels. The second outcomes include serum IgE levels, inflammatory cell profiles within the nasal mucosa, and postoperative complications.

Timeline

Start
2026-04-11
Primary completion
2027-04-01
Completion
2027-04-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Mometasone furoate Other / unclassified 50 ug Intranasal

Indications