drugset / Trial / NCT07528690

Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)

NCT07528690

Phase 2 Not yet recruiting 162 enrolled VA Office of Research and Development
RandomizedParallel-groupQuadruple-blindPrevention

Summary

The goal of this clinical trial is to find out whether changing the microbes in the bowels of Veterans with cirrhosis and hepatic encephalopathy (a condition that affects the brain as a result of liver problems) using capsules made from microbes from healthy people can prevent future episodes of hepatic encephalopathy.

Timeline

Start
2026-10-30
Primary completion
2030-10-31
Completion
2031-03-03

Drugs

EvaluationDrugModalityDoseRoute
Subject MTP-101C Other / unclassified Oral