drugset / Trial / NCT07544784

AK104 Plus Radiotherapy Combined With Standard Therapy Versus Standard Therapy as First-Line Treatment for pMMR/MSS CRLM (APSOC)

NCT07544784

Phase 2 Recruiting 73 enrolled Fudan University
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a prospective, randomized controlled, single-center phase II clinical study. It aims to compare the efficacy of AK104 plus radiotherapy combined with standard therapy versus standard therapy as first-line treatment for liver metastases from metastatic colorectal cancer.

Timeline

Start
2025-11-04
Primary completion
2027-12-01
Completion
2028-11-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cadonilimab Monoclonal antibody