drugset / Trial / NCT07548606
A Drug-Drug Interaction Study of Itraconazole and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-017)
Non-randomizedSequentialOpen-labelBasic science
Summary
Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer. The purpose of this study is to learn what happens to opevesostat in a person's body over time (a pharmacokinetic or PK study). Researchers will compare what happens to opevesostat in the body when it is given with and without another medicine called itraconazole.
Timeline
- Start
- 2026-05-11
- Primary completion
- 2026-06-01
- Completion
- 2026-06-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | — | Oral |
| Subject | Opevesostat | Small molecule | — | Oral |
| Background | Fludrocortisone | Other / unclassified | — | Oral |
| Background | Prednisone | Other / unclassified | — | Oral |
Indications
No indication recorded.