drugset / Trial / NCT07549698

Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease

NCT07549698 ↗

Phase 1/2 Recruiting 60 enrolled CRISPR Therapeutics AG
NaSingle-groupOpen-labelTreatment

Summary

This is a single-arm, open-label, multicenter, ascending dose Phase 1/2 trial evaluating the safety and preliminary efficacy of CTX112 or Zugocabtagene geleucel (zugo-cel) in adult participants with relapsed/refractory primary Immune Thrombocytopenia (ITP) and relapsed/refractory primary Warm Autoimmune Hemolytic Anemia (wAIHA).

Timeline

Start
2026-06
Primary completion
2033-12
Completion
2033-12

Drugs

EvaluationDrugModalityDoseRoute
Subject CTX112 Cell therapy — Intravenous