drugset / Trial / NCT07560124

A Study of AK138D1 Alone or in Combination With Ivonescimab in Advanced Breast Cancer

NCT07560124

Phase 1/2 Not yet recruiting 286 enrolled Akeso
RandomizedParallel-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to evaluate the safety, tolerability, and efficacy of AK138D1 as monotherapy or in combination with ivonescimab in patients with advanced breast cancer. Participants will receive study treatment with AK138D1 alone or in combination with ivonescimab, undergo safety assessments and tumor evaluations, and be followed for treatment tolerability, antitumor activity, and clinical outcomes.

Timeline

Start
2026-06-06
Primary completion
2028-06-06
Completion
2030-09-14

Drugs

EvaluationDrugModalityDoseRoute
Subject AK138D1 Unknown Intravenous
Subject Ivonescimab Monoclonal antibody Intravenous

Indications