drugset / Trial / NCT07563036

JAK2 Expression in Androgenetic Alopecia Before and After Topical Minoxidil

NCT07563036

Recruiting 25 enrolled Kasr El Aini Hospital
NaSingle-groupOpen-labelTreatment

Summary

Androgenetic alopecia is a common form of progressive hair loss. This prospective single-arm pre-post interventional study aims to assess tissue Janus Kinase 2 (JAK2) expression in patients with androgenetic alopecia by comparing balding and non-balding scalp at baseline, and to evaluate changes in JAK2 expression in balding scalp after 3 months of topical minoxidil 5% therapy. Clinical response will be assessed using standardized trichoscopic parameters.

Timeline

Start
2026-02-01
Primary completion
2026-10-01
Completion
2027-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Minoxidil Small molecule 1 ml Topical
Subject Minoxidil Small molecule 5 % Topical

Indications