drugset / Trial / NCT07566897

A Phase I Study to Evaluate the Safety and Efficacy of L19IL2 in Combination With Ruxolitinib in Patients With Advanced Solid Tumors

NCT07566897

Phase 1 Not yet recruiting 96 enrolled Philogen S.p.A.
Non-randomizedSequentialOpen-labelTreatment

Summary

This trial aims to address unmet medical needs in advanced solid tumors, specifically metastatic clear cell renal carcinoma, locally advanced or metastatic pancreatic adenocarcinoma, and metastatic colorectal adenocarcinoma.

Timeline

Start
2026-05-01
Primary completion
2029-12
Completion
2030-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Darleukin Protein / enzyme biologic Intravenous
Subject Ruxolitinib Small molecule 10 mg Oral