Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical Trial

Summary

The aims of this clinical trial will test whether or not the onset of nearsightedness is delayed in a group of children randomized to nightly drops in 0.05% atropine in both eyes, in comparison to children who receiving nightly placebo drops in both eyes. The primary outcome is the two-year cumulative incidence of nearsightedness. The second aim of this project will determine whether atropine is associated with slower eye growth in children receiving nightly drops of atropine versus placebo.

Timeline

Start

2026-05-27

Primary completion

2028-05-15

Completion

2028-05-15

Drugs

Indications