drugset / Trial / NCT07570654

Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

NCT07570654

Phase 2/3 Not yet recruiting 300 enrolled COMPASS Pathways
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The Redefine Study (COMP202) is testing COMP360 to see if it may reduce post-traumatic stress disorder (PTSD) symptoms when administered alongside monitoring and support from a trained study team. COMP360 is a lab-made form of the naturally occurring chemical compound psilocybin.

Timeline

Start
2026-09
Primary completion
2028-11
Completion
2029-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Psilocybin Other / unclassified 1 mg
Subject Psilocybin Other / unclassified 10 mg
Subject Psilocybin Other / unclassified 25 mg