drugset / Trial / NCT07570953

A Study Of Synthetic THC And Sleep

NCT07570953

Phase 2/3 Not yet recruiting 72 enrolled Mayo Clinic
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine if oral dronabinol prior to sleep can improve CPAP adherence and sleep quality in humans. We also seek to determine if combination therapy of CPAP and pre-sleep dronabinol is associated with improved BP regulation. We will also explore BP regulatory mechanisms and whether these are impacted differently between traditional CPAP therapy and combination CPAP/dronabinol.

Timeline

Start
2026-09
Primary completion
2028-04
Completion
2028-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Dronabinol Other / unclassified 10 mg Oral