Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation

Summary

Study of QUAIL-100 in Patients With High Risk Acute Leukemia and Myelodysplastic Syndrome Who Have Received Hematopoietic Stem Cell Transplant

Timeline

Start

2026-06

Primary completion

2028-06

Completion

2029-03

Publications

• Background Chevee V, Lobanovska M, Rivera-Lugo R, Guereca L, Feng Y, Anaya-Sanchez A, Garcia Castillo J, Huckins AM, Lemmens EE, Rae CS, Hardy JW, Carrington R, Kotula JW, Portnoy DA. Reprogramming Listeria monocytogenes flavin metabolism to improve its therapeutic safety profile and broaden innate T-cell activation. mBio. 2026 Feb 11;17(2):e0365225. doi: 10.1128/mbio.03652-25. Epub 2025 Dec 31.

Drugs

Indications