A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder

Summary

The main purpose of this study is to assess how well the study drug (JNJ-42847922) works (efficacy) compared with placebo in improving depressive symptoms in participants with major depressive disorder (\[MDD\], a common mood disorder that causes a lasting feeling of sadness and a loss of interest in everyday activities) in double-blind treatment phase. Further, to evaluate long-term safety and tolerability of JNJ-42847922 in participants with MDD in the open label treatment phase.

Timeline

Start

2026-04-30

Primary completion

2028-08-24

Completion

2029-05-03

Drugs

Indications