drugset / Trial / NCT07577856

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis

NCT07577856

Phase 3 Recruiting 644 enrolled Janssen Research & Development, LLC
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to guselkumab at Week 48 in participants with moderately to severely active ulcerative colitis (UC, a chronic disease of the large intestine in which the lining of the colon becomes inflamed and develops ulcers).

Timeline

Start
2026-05-23
Primary completion
2028-08-11
Completion
2030-10-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Guselkumab Monoclonal antibody Subcutaneous
Subject JNJ-78934804 Unknown Subcutaneous

Indications