drugset / Trial / NCT07583654

Safety, Tolerability, and Preliminary Antitumor Activity of Cationic Peptide-IL22BP mRNA in Advanced Solid Tumors

NCT07583654 ↗

Phase 1 Recruiting 18 enrolled West China Hospital
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The goal of this phase 1 clinical trial is to evaluate the safety, tolerability, and preliminary antitumor activity of a peptide-delivered IL-22BP biotherapy in patients with advanced solid tumors. The main questions it aims to answer are: Is the IL-22BP formulation safe and tolerable? Does the IL-22BP formulation show preliminary antitumor activity?

Timeline

Start
2026-07-13
Primary completion
2027-06-30
Completion
2027-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject CP-IL22BP mRNA Messenger RNA (mRNA) — Other