drugset / Trial / NCT07586124

Pucotenlimab Plus Becotatug Vedotin in Perioperative Treatment of Locally Advanced Resectable Head and Neck Squamous Cell Carcinoma

NCT07586124

Phase 2 Recruiting 80 enrolled Lepu Biopharma Co., Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

A multicenter, randomized, double-blind, phase II clinical study designed to evaluate the safety, pharmacokinetics, and preliminary efficacy of Becotatug Vedotin for Injection in combination with PD-1 in patients with locally advanced resectable head and neck squamous cell carcinoma

Timeline

Start
2026-07-06
Primary completion
2027-12
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Becotatug Vedotin Monoclonal antibody Intravenous
Background Pucotenlimab Monoclonal antibody Intravenous