drugset / Trial / NCT07588139
A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult Participants
Non-randomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the interstitial concentrations using the open-flow microperfusion device and plasma pharmacokinetics following multiple doses of povorcitinib or topical ruxolitinib cream in healthy adult participants.
Timeline
- Start
- 2026-05-18
- Primary completion
- 2026-09-03
- Completion
- 2026-09-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Povorcitinib | Small molecule | — | Oral |
| Subject | Ruxolitinib | Small molecule | — | Topical |
Indications
No indication recorded.