A Trial of Upadacitinib for Non-responsive Eosinophilic Esophagitis

Summary

The goal of this study is to find out if a medication called upadacitinib can help treat a condition called Eosinophilic Esophagitis (EoE). The main question it aims to answer are: \- Does upadacitinib in addition to topical corticosteroids help reduce EoE disease activity? Participants will: * Take upadacitinib or placebo every day for 12 weeks, followed by 12 weeks of upadacitinib * Fill out surveys and answer health questions * Visit the clinic every 4 weeks for checkups and tests

Timeline

Start

2026-07

Primary completion

2030-02

Completion

2030-06

Drugs

Indications