drugset / Trial / NCT07590531

AMT-116 in Combination With Ivosidan in Patients With Lung Cancer

NCT07590531

Phase 1/2 Recruiting 118 enrolled Multitude Therapeutics Inc.
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and efficacy of AMT-116 in combination with ivosidan (AK112) in patients with advanced non-small cell lung cancer (NSCLC). The study is divided into two parts: the part I is dose escalation and the Part Ⅱ for expansion.

Timeline

Start
2026-06-29
Primary completion
2027-05-30
Completion
2027-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject AMT-116 Other / unclassified
Subject Ivonescimab Monoclonal antibody