drugset / Trial / NCT07591883
Spatiotemporal Evolution of Traditional Chinese Medicine Mechanisms in Acute Ischemic Stroke Treated With Dengzhan Xixin and Dengzhan Shengmai
Phase 2/3
Not yet recruiting
358 enrolled
Guangdong Provincial Hospital of Traditional Chinese Medicine
Nanfang Hospital, Southern Medical University · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
To integrate large-scale RCT data on clinical symptoms, TCM syndromes, prognosis, and multi-omics profiles, construct a spatiotemporal dynamic network for disease-syndrome evolution of acute ischemic stroke (AIS) in the acute and recovery phases, evaluate the efficacy and safety of sequential treatment with Erigeron breviscapus-Dengzhan Shengmai for AIS, and provide evidence for precise syndrome differentiation and individualized therapy.Secondary Objective:To investigate the optimal time window and key intervention targets of sequential treatment with Erigeron breviscapus-Dengzhan Shengmai for AIS.
Timeline
- Start
- 2026-06-01
- Primary completion
- 2029-07-30
- Completion
- 2029-07-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dengzhan Shengmai | Traditional medicine (herbal / TCM) | 0.36 g | Oral |
| Subject | Erigeron breviscapus | Unknown | 40 ml | Intravenous |