RP-008 in Combination With Daily Oral Varenicline for the Treatment of Trigeminal Neuralgia

Summary

The goal of this study is to evaluate if KRIYA-748 (RP-008) is safe, tolerable, and preliminary effective in treating trigeminal neuralgia (TN) when used in combination with varenicline tartrate. The study will also assess what doses of RP-008 are safe and tolerable for participants and how the severity of participants' TN pain and frequency of facial pain attacks are affected.

Timeline

Start

2026-08

Primary completion

2029-02

Completion

2029-02

Drugs

Indications