drugset / Trial / NCT07600177
Mavacamten to Aficamten Transition in Patients With Obstructive Hypertrophic Cardiomyopathy
Phase 4
Recruiting
40 enrolled
Oregon Health and Science University
Cytokinetics · collabSaint Lukes Hospital Mid America Heart Institute · collab
NaSingle-groupOpen-labelTreatment
Summary
This is an investigator-initiated two-center study. The goal of this study is to investigate the feasibility, safety and efficacy outcomes of a seamless transition from mavacamten to aficamten in patients with obstructive hypertrophic cardiomyopathy (oHCM).
Timeline
- Start
- 2026-05-05
- Primary completion
- 2026-12-31
- Completion
- 2027-03-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aficamten | Small molecule | — | — |