Anakinra Rescue Treatment for Moderate Asthma Attacks (ARTMA)

Summary

In this single center, interventional pilot study, 40 participants at high risk for future exacerbation will be randomized to anakinra (v. placebo control) treatment for home administration as part of an asthma action plan (AAP) and monitored through their first moderate asthma exacerbation, triggering treatment dosing over a 26 week period. Key feasibility questions will be assessed in this pilot study to inform trial design and sample size selection for a future multi-site phase II clinical trial testing anakinra as a rescue treatment for moderate asthma exacerbations.

Timeline

Start

2026-11-01

Primary completion

2029-01-01

Completion

2029-01-01

Drugs

Indications