drugset / Trial / NCT07601243

Study of GS-2426 in Participants With Advanced Solid Tumors

NCT07601243 ↗

Phase 1 Recruiting 174 enrolled Gilead Sciences
Non-randomizedSequentialOpen-labelTreatment

Summary

The goal of this clinical study is to learn more about the study drug GS-2426, and how safe and tolerable it is in participants with advanced methylthioadenosine phosphorylase (MTAP)-deleted solid tumors. The primary objective of this study is to evaluate the safety and tolerability of GS-2426 in participants with MTAP-deleted advanced solid tumors and to determine the maximum tolerated dose (MTD)/maximum administered dose (MAD) and the recommended phase II dose (RP2D).

Timeline

Start
2026-06-02
Primary completion
2029-01
Completion
2029-01

Drugs

EvaluationDrugModalityDoseRoute
Subject GS-2426 Unknown — Oral

Indications