drugset / Trial / NCT07602127

Safety and Efficacy Study of Novel Gene Therapy AGX-08 for Geographic Atrophy

NCT07602127 ↗

Phase 0 Not yet recruiting 24 enrolled Zhongmou Therapeutics
RandomizedParallel-groupDouble-blindTreatment

Summary

This is AGX-08's safety, tolerability, and efficacy in Geographic Atrophy first-in-human study. This trial is meant to evaluate the safety and efficacy of AGX-08 in Geographic Atrophy patients. Unilateral intravitreal injections (IVT) will be given into the subject's Study Eye.

Timeline

Start
2026-07-01
Primary completion
2028-12-30
Completion
2029-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject AGX-08 Gene therapy (AAV / viral vector) — Intravitreal