drugset / Trial / NCT07603713
Efficacy and Safety of LP-005 Injection in Patients With Moderate-to-Severe Periodontitis
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical study designed to evaluate the clinical efficacy, safety, pharmacokinetics, pharmacodynamics, and immunogenicity of multiple local injections of different doses of LP-005 injection in patients with moderate-to-severe periodontitis, and to investigate changes in biomarker levels.
Timeline
- Start
- 2026-05-01
- Primary completion
- 2026-11-12
- Completion
- 2027-03-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LP-005 | Protein / enzyme biologic | 2.5 mg | Other |
| Subject | LP-005 | Protein / enzyme biologic | 5 mg | Other |
| Subject | LP-005 | Protein / enzyme biologic | 7.5 mg | Other |