drugset / Trial / NCT07608666

Study to Evaluate the Effect of Rabeprazole Sodium Enteric-coated Tablets on the Pharmacokinetics of TQ05105 Tablets

NCT07608666

Phase 1 Not yet recruiting 17 enrolled Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
NaSequentialOpen-labelOther

Summary

Primary objective: To evaluate the effect of rabeprazole on the primary pharmacokinetics of TQ05105 tablets. Secondary objective: To assess the safety and tolerability of single oral administration of TQ05105 tablets alone and in combination with rabeprazole in healthy study participants. To evaluate the effect of rabeprazole on the secondary PK parameters of TQ05105 and the pharmacokinetics of its active metabolite TQ12550.

Timeline

Start
2026-07
Primary completion
2026-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Rabeprazole Small molecule
Subject TQ05105 Small molecule Oral

Indications